Kamakura, Japan

Akira Shimamoto



Average Co-Inventor Count = 3.7

ph-index = 4

Forward Citations = 35(Granted Patents)


Location History:

  • Kanagawa, JP (2002 - 2006)
  • Horoshima, JP (2012)
  • Hiroshima, JP (2012 - 2013)
  • Kamakura, JP (2008 - 2014)

Company Filing History:


Years Active: 2002-2014

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11 patents (USPTO):Explore Patents

Title: Akira Shimamoto: Innovator in Cancer Research

Introduction

Akira Shimamoto is a prominent inventor based in Kamakura, Japan, known for his significant contributions to cancer research. With a total of 11 patents, he has made remarkable strides in developing innovative solutions for cancer treatment.

Latest Patents

One of his latest patents focuses on an apoptosis inducer for cancer cells. This invention reveals that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells, thereby suppressing their proliferation. The compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are believed to have the activity of inducing apoptosis. Another significant patent involves cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes. The present inventors discovered that inhibiting the expression of various genes associated with chromosome stabilization induces cancer cell-specific apoptosis and inhibits cell proliferation. Compounds that inhibit the expression of a gene associated with chromosome stabilization or inhibit the function of a protein encoded by such a gene are thought to have cancer cell-specific apoptosis-inducing effects.

Career Highlights

Throughout his career, Akira has worked with notable organizations, including Genecare Research Institute Co., Ltd. and Agene Research Institute Co., Ltd. His work has been instrumental in advancing the understanding of cancer biology and developing targeted therapies.

Collaborations

Akira has collaborated with esteemed colleagues, including Yasuhiro Furuichi and Motoki Takagi, to further enhance the impact of his research in the field of cancer treatment.

Conclusion

Akira Shimamoto's innovative work in cancer research has led to significant advancements in the development of targeted therapies. His contributions continue to inspire future research and innovation in the fight against cancer.

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