The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2012
Filed:
Nov. 17, 2005
Motoki Takagi, Shinagawa-ku, JP;
Akira Shimamoto, Horoshima, JP;
Yasuhiro Furuichi, Kamakura, JP;
Ayumi Sato, Yokohama, JP;
Motoki Takagi, Shinagawa-ku, JP;
Akira Shimamoto, Horoshima, JP;
Yasuhiro Furuichi, Kamakura, JP;
Ayumi Sato, Yokohama, JP;
Genecare Research Institute Co., Ltd., Kamakura-shi, JP;
Abstract
The present inventors discovered that although suppressing expression of the RecQ1 gene, a RecQ helicase family gene, shows suppressive effects on cell proliferation in cancer cells, such effects are not observed in human TIG3 cells (a normal diploid fibroblast cell line), which are normal cells. Hence, the present inventors discovered that siRNAs against RecQ1 gene have cancer cell-specific cell proliferation-suppressing effects that are mediated by suppression of the expression of said gene.