The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
May. 16, 2012
Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes
Applicants:
Motoki Takagi, Shinagawa-ku, JP;
Kazunobu Futami, Fujisawa, JP;
Akira Shimamoto, Hiroshima, JP;
Yasuhiro Furuichi, Kamakura, JP;
Inventors:
Motoki Takagi, Shinagawa-ku, JP;
Kazunobu Futami, Fujisawa, JP;
Akira Shimamoto, Hiroshima, JP;
Yasuhiro Furuichi, Kamakura, JP;
Assignee:
Genecare Research Institute Co., Ltd., Kanagawa, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/00 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present inventors discovered that inhibition of the expression of various genes associated with chromosome stabilization induces cancer cell-specific apoptosis and inhibits cell proliferation. Compounds that inhibit expression of a gene associated with chromosome stabilization or inhibit the function of a protein encoded by such a gene are thought to have cancer cell-specific apoptosis-inducing effects.