The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Sep. 27, 2012
Applicant:
Genecare Research Institute Co., Ltd., Kanagawa, JP;
Inventors:
Motoki Takagi, Kamakura, JP;
Akira Shimamoto, Kamakura, JP;
Yasuhiro Furuichi, Kamakura, JP;
Ayumi Sato, Kamakura, JP;
Assignee:
Genecare Research Institute Co., Ltd., Kamakura-shi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention revealed that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells and their proliferation is suppressed. Compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are thought to have the activity of inducing apoptosis.