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For the Inventor, By the Inventor

Gulph Mills, PA, United States of America

L.e.a.f. Holdings Group LLC

Calculating rank
USPTO Granted Patents = 30


Forward Citations = 125

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6 inventors (with patents filed for the assignee):

goldMedal Clet Niyikiza (30 out of 38 patents)

silverMedal Victor Mandla Moyo (30 out of 44 patents)

bronzeMedal Zhenghong Xu (3 out of 3 patents)

4.  Kaniz Khalifa (3 out of 3 patents)

5.  Bolin Geng (1 out of 1 patent)

6.  Gwangseong Kim (1 out of 1 patent)

7.  Jose Varghese (0 patent)


Core Competencies:
Trans-Crocetin
Carotenoid Compositions
Alpha Polyglutamated Pemetrexed
Gamma Polyglutamated Aminopterin
Polyglutamated Antifolates
Targeted Liposomal Gemcitabine
Platinum Complexes
Alpha Polyglutamated Raltitrexed
Gamma Polyglutamated Pemetrexed
Tetrahydrofolates
Lometrexol
Pralatrexate

30 patents:

1. 12622874 - Trans-crocetin compositions and treatment regimens (2026-05-12),
2. 12458597 - Carotenoid compositions and uses thereof (2025-11-04),
3. 12433893 - Alpha polyglutamated pemetrexed and uses thereof (2025-10-07),
4. 12350271 - Gamma polyglutamated aminopterin and uses thereof (2025-07-08),
5. 12336994 - Alpha polyglutamated tetrahydrofolates and uses thereof (2025-06-24),
6. 12310966 - Alpha polyglutamated aminopterin and uses thereof (2025-05-27),
7. 12296022 - D glutamate polyglutamated antifolates and uses thereof (2025-05-13),
8. 12290518 - Gamma polyglutamated methotrexate and uses thereof (2025-05-06),
9. 12246019 - Alpha polyglutamated lometrexol and uses thereof (2025-03-11),
10. 12246018 - Gamma polyglutamated pemetrexed and uses thereof (2025-03-11),
11. 12246015 - Alpha polyglutamated raltitrexed and uses thereof (2025-03-11),
12. 12239734 - Gamma polyglutamated raltitrexed and uses thereof (2025-03-04),
13. 12220431 - Gamma polyglutamated antifolates and uses thereof (2025-02-11),
14. 12213981 - Alpha polyglutamated pralatrexate and uses thereof (2025-02-04),
15. 12201695 - Polyglutamated pemetrexed and uses thereof (2025-01-21),
Company Overview
L.e.a.f. Holdings Group LLC, based in Gulph Mills, PA, specializes in innovative solutions across various sectors, focusing on sustainable technologies and advanced materials. The company is dedicated to developing products that enhance efficiency and reduce environmental impact, leveraging cutting-edge research in fields such as renewable energy and eco-friendly manufacturing processes. With a commitment to fostering sustainable practices, L.e.a.f. Holdings Group aims to contribute positively to both industry and society.
Profile summary synthesized from public USPTO records and patent filings.

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USPTO Data Jan 1 1976 - Oct 27 2026

30 Patents

#1 in Gulph Mills, PA

#406 in Pennsylvania

#11,288 in US

#21,924 in the World

Gulph Mills, PA (US)
Gulph Mills, PA, United States of America

L.e.a.f. Holdings Group LLC

Forward Citations = 125

6 inventors:

goldMedal Clet Niyikiza (30 out of 38 patents)

silverMedal Victor Mandla Moyo (30 out of 44 patents)

bronzeMedal Zhenghong Xu (3 out of 3 patents)

4.  Kaniz Khalifa (3 out of 3 patents)

5.  Bolin Geng (1 out of 1 patent)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: L.e.a.f. Holdings Group LLC. Retrieved from https://idiyas.com/company/l-e-a-f-holdings-group

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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