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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12220431 B1

PDFFull Text
Date of Patent:
Feb. 11, 2025

Filed:

Feb. 07, 2019

Gamma polyglutamated antifolates and uses thereof

Applicant:

L.e.a.f. Holdings Group Llc, Gulph Mills, PA (US);

Inventors:

Clet Niyikiza, Gulph Mills, PA (US);

Victor Mandla Moyo, Ringoes, NJ (US);

Assignee:

L.E.A.F. HOLDINGS GROUP LLC, Gulph Mills, PA (US);

Attorney:

Nixon & Vanderhye, PC

Primary Examiner:

Brian J Davis

Int. Cl.
CPC ...
A61K 33/243 (2019.01); A61K 9/127 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61K 47/55 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 33/243 (2019.01); A61K 9/127 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61K 47/55 (2017.08); A61K 47/6803 (2017.08); A61P 35/00 (2018.01);
Abstract

The disclosure relates generally to gamma polyglutamated Antifolate, formulations containing liposomes filled with gamma polyglutamated Antifolate, methods of making the gamma polyglutamated Antifolate and liposome containing formulations, and methods of using polyglutamated gamma polyglutamated Antifolate and liposome containing formulations to treat hyperproliferative disorders (e.g., cancer) and disorders of the immune system (e.g., inflammation and an autoimmune disease such as rheumatoid arthritis).

Find Patent Forward Citations

Niyikiza, Clet. (2025). Gamma polyglutamated antifolates and uses thereof (U.S. Patent No. 12220431). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12220431

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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