The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
May. 03, 2019
L.e.a.f. Holdings Group Llc, Gulph Mills, PA (US);
Clet Niyikiza, Gulph Mills, PA (US);
Victor Mandla Moyo, Ringoes, NJ (US);
Bolin Geng, Gulph Mills, PA (US);
Zhenghong Xu, Gulph Mills, PA (US);
Kaniz Khalifa, Gulph Mills, PA (US);
Gwangseong Kim, Gulph Mills, PA (US);
L.E.A.F. HOLDINGS GROUP LLC, Gulph Mills, PA (US);
Abstract
Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, disorders and conditions associated with, but not limited to, infection, endotoxemia, inflammation, sepsis, ischemia, hypoxia, shock, stroke, lung injury, wound healing, traumatic injury, reperfusion injury, cardiovascular disease, kidney disease, liver disease, inflammatory disease, metabolic disease, pulmonary disorders, blood related disorders and hyperproliferative diseases such as cancer. Methods of making, delivering, and using the pharmaceutical compositions are also provided.