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La Jolla, CA, United States of America

Advanced Tissue Sciences, Inc.

USPTO Granted Patents = 40

CIPO Patents = 1

Trademarks = 1

Forward Citations = 3,986

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38 inventors (with patents filed for the assignee):

Gail K Naughton (24 out of 48 patents)

Brian A Naughton (23 out of 29 patents)

Alvin Edward Peterson (5 out of 7 patents)

4. Lee K Landeen (4 out of 9 patents)

5. Benson Sibanda (4 out of 4 patents)

6. Mark A Applegate (4 out of 11 patents)

7. Noushin Dunkelman (4 out of 4 patents)

8. Anthony F Purchio (4 out of 5 patents)

9. Joan Zeltinger (3 out of 24 patents)

10. James H Flatt (3 out of 5 patents)

11. Craig R Halberstadt (3 out of 3 patents)

12. John W Bennett (3 out of 3 patents)

13. Mark Baumgartner (2 out of 9 patents)

14. Kang Liu (2 out of 2 patents)

15. Jonathan N Mansbridge (2 out of 9 patents)

Core Competencies:

Cell Culture

Extracellular Matrix

Three-Dimensional Tissue

Bioreactor

Cartilage Repair

Wound Healing

Stromal Cells

Gene Up-Regulation

Tendon Function

Liver Cells

Blood-Brain Barrier

Pancreatic Cells

40 patents: Sort by Forward Citations

1. 6381981 - Container for shipping and storing frozen products (2002-05-07),

2. 6372494 - Methods of making conditioned cell culture medium compositions (2002-04-16),

3. 6291240 - Cells or tissues with increased protein factors and methods of making and using same (2001-09-18),

4. 6284284 - Compositions and methods for production and use of an injectable naturally secreted extracellular matrix (2001-09-04),

5. 6218182 - Method for culturing three-dimensional tissue in diffusion gradient bioreactor and use thereof (2001-04-17),

6. 6140039 - Three-dimensional filamentous tissue having tendon or ligament function (2000-10-31),

7. 6121042 - Apparatus and method for simulating in vivo conditions while seeding and (2000-09-19),

8. 6060306 - Apparatus and method for sterilizing, seeding, culturing, storing, (2000-05-09),

9. 6027935 - Gene up-regulated in regenerating liver (2000-02-22),

10. 6022743 - Three-dimensional culture of pancreatic parenchymal cells cultured (2000-02-08),

11. 6008049 - Diffusion gradient bioreactor and extracorporeal liver device (1999-12-28),

12. 5962325 - Three-dimensional stromal tissue cultures (1999-10-05),

13. 5928945 - Application of shear flow stress to chondrocytes or chondrocyte stem (1999-07-27),

14. 5902741 - Three-dimensional cartilage cultures (1999-05-11),

15. 5863531 - In vitro preparation of tubular tissue structures by stromal cell (1999-01-26),

Company Overview

Advanced Tissue Sciences, Inc., based in La Jolla, California, specializes in the development and manufacturing of innovative solutions in regenerative medicine. The company focuses on advanced cell culture techniques and the creation of extracellular matrices, which are crucial for tissue engineering applications. Their expertise extends to the use of diffusion gradient bioreactors and the cultivation of three-dimensional tissues, particularly for skin wound healing and the application of chondrocyte stem cells in regenerative therapies.

Profile summary synthesized from public USPTO records and patent filings.

Company Badge

USPTO Data Jan 1 1976 - Oct 20 2026

40 Patents

#16 in La Jolla, CA

#2,041 in California

#8,616 in US

#17,087 in the World

La Jolla, CA, United States of America

Advanced Tissue Sciences, Inc.

Forward Citations = 3,986

38 inventors:

Gail K Naughton (24 out of 48 patents)

Brian A Naughton (23 out of 29 patents)

Alvin Edward Peterson (5 out of 7 patents)

4. Lee K Landeen (4 out of 9 patents)

5. Benson Sibanda (4 out of 4 patents)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: Advanced Tissue Sciences, Inc.. Retrieved from https://idiyas.com/company/advanced-tissue-sciences

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]

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