Craig R Halberstadt

Title: Innovations by Craig R Halberstadt in Tissue Engineering

Introduction

Craig R Halberstadt is a notable inventor based in La Jolla, California. He has made significant contributions to the field of tissue engineering, holding three patents that focus on innovative methods for culturing three-dimensional tissue. His work is particularly relevant in the development of bioreactors that enhance the growth and functionality of liver tissue.

Latest Patents

One of Halberstadt's latest patents is titled "Method for culturing three-dimensional tissue in diffusion gradient bioreactor and use thereof." This invention describes a tissue engineering bioreactor designed for growing three-dimensional tissue. In this bioreactor, cells are seeded onto a mesh and are provided with two media flows, each contacting a different side of the cells. The media flows contain varying concentrations of nutrients, allowing for nutrient delivery to the cells through a diffusion gradient. This bioreactor can be utilized to grow liver tissue and is designed as an extracorporeal liver assist device. In this device, blood or plasma from a patient is directed to flow against the three-dimensional liver tissue, while the tissue is simultaneously exposed to media that provides essential nutrients and gases. The device features porous boundaries between the blood or plasma, tissue, and media, facilitating nutrient and protein delivery by diffusion gradient to effectively dialyze a patient's blood.

Another significant patent by Halberstadt is the "Diffusion gradient bioreactor and extracorporeal liver device." This invention shares similar principles with his previous patent, focusing on the cultivation of three-dimensional tissue. The bioreactor's design allows for the effective growth of liver tissue, which can be critical in medical applications, particularly for patients requiring liver support.

Career Highlights

Halberstadt's career is marked by his role at Advanced Tissue Sciences, Inc., where he has been instrumental in advancing tissue engineering technologies. His innovative approaches have contributed to the development of devices that can potentially improve patient outcomes in liver-related medical conditions.

Collaborations

Throughout his career, Halberstadt has collaborated with notable colleagues, including Brian A Naughton and Benson Sibanda. These collaborations have fostered a productive environment for innovation and research in the field of tissue engineering.

Conclusion

Craig R Halberstadt's contributions to tissue engineering through his patents and work at Advanced Tissue Sciences, Inc. highlight the importance of innovation in medical