Company Filing History:
Years Active: 2024-2025
Title: Ziyang He: Innovator in mRNA Vaccine Technology
Introduction
Ziyang He is a prominent inventor based in Potomac, MD (US), known for his significant contributions to the field of mRNA vaccine technology. With a total of 2 patents, he has been at the forefront of developing innovative solutions to combat viral infections, particularly those caused by coronaviruses.
Latest Patents
Ziyang He's latest patents include groundbreaking compositions and methods for mRNA vaccines against novel coronavirus infections. One of his patents provides a ribonucleic acid (RNA) encoding a spike (S) protein or an immunogenic fragment thereof of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which includes at least one non-naturally occurring amino acid mutation. In some embodiments, the S protein is derived from a delta variant. Additionally, this patent outlines relevant polynucleotides, vectors, cells, compositions, kits, production methods, and methods of use. Another patent focuses on potent mRNA vaccines for the prevention and treatment of 2019 novel Coronavirus (2019-nCoV) infections. This composition includes a pharmaceutical formulation containing one or more mRNA molecules encoding spike protein epitopes, including mutated epitopes, or mRNA cocktails that encode critical viral genes, along with pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Methods for stimulating systemic immune responses and treatment are also provided, including subcutaneous, intraperitoneal, and intramuscular injections.
Career Highlights
Ziyang He is currently associated with Rnaimmune, Inc., where he continues to advance his research and development efforts in the field of mRNA technology. His work has been instrumental in addressing the challenges posed by emerging viral threats.
Collaborations
Ziyang He collaborates with notable colleagues, including Shenggao Tang and Dong Shen, who contribute to his research endeavors and the development of innovative vaccine solutions.
Conclusion
Ziyang He is a key figure in the advancement of mRNA vaccine technology, with a focus on combating novel coronavirus infections. His innovative patents and ongoing research efforts are paving the way for effective vaccine solutions in the fight against viral diseases.