The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2024

Filed:

Feb. 08, 2021
Applicant:

Rnaimmune, Inc., Gaithersburg, MD (US);

Inventors:

Shenggao Tang, Guangzhou, CN;

Dong Shen, Baltimore, MD (US);

Chun Lu, Montreal, CA;

Ziyang He, Potomac, MD (US);

Jiaxi He, Baltimore, MD (US);

Patrick Y. Lu, Potomac, MD (US);

Assignee:

RNAimmune, Inc., Germantown, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61P 31/14 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61M 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 9/0019 (2013.01); A61K 9/5123 (2013.01); A61P 31/14 (2018.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/544 (2013.01); A61K 2039/55555 (2013.01); A61M 11/00 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/20071 (2013.01);
Abstract

Compositions and methods are provided for potent mRNA vaccines for prevention and treatment of 2019 novel Coronavirus (2019-nCoV) infections. The compositions include a pharmaceutical composition containing one or more mRNA molecules encoding spike protein epitopes, including mutated epitopes, or mRNA cocktails that encode critical viral genes together with pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Methods for stimulating system immune responses and treatment are provided, including subcutaneous, intraperitoneal and intramuscular injections.


Find Patent Forward Citations

Loading…