Company Filing History:
Years Active: 2006-2008
Title: Zihni Bilgicer: Innovator in Fluorinated Peptides
Introduction
Zihni Bilgicer is a notable inventor based in Somerville, MA (US). He has made significant contributions to the field of biochemistry, particularly in the development of fluorinated peptides. With a total of 2 patents, his work has implications for protein stability and design.
Latest Patents
Bilgicer's latest patents include "Non-racemic trifluoroleucine, and methods of making and using" and "Non-racemic hexafluoroleucine, and methods of making and using." One aspect of the first invention relates to hexafluoroleucine and congeners thereof, along with methods for synthesizing these compounds. Another aspect focuses on the synthesis of protein cores that incorporate hexafluoroleucine. Comparative biophysical studies have characterized certain peptides containing hexafluoroleucine, revealing that these fluorinated peptides exhibit higher thermal stability and enhanced resistance to chemical denaturation. Additionally, mixed hydrocarbon-fluorocarbon cores self-sort into homogeneous bundles, suggesting new avenues for the design and manipulation of protein-protein interfaces.
Career Highlights
Bilgicer is affiliated with Tufts College, where he continues to advance research in his field. His innovative work has garnered attention for its potential applications in biochemistry and molecular biology.
Collaborations
He has collaborated with notable colleagues such as Alfio Fichera and Krishna Kumar, contributing to a dynamic research environment.
Conclusion
Zihni Bilgicer's contributions to the field of fluorinated peptides highlight his innovative spirit and dedication to advancing scientific knowledge. His patents pave the way for future research and applications in protein design and stability.