Zhongyi Cheng

Title: Innovations of Zhongyi Cheng in Enzyme Engineering

Introduction

Zhongyi Cheng is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of enzyme engineering, particularly through his innovative work on nitrile hydratase. His research has implications for industrial production processes, showcasing the potential of enzyme mutants in enhancing efficiency.

Latest Patents

Zhongyi Cheng holds a patent for a mutant of nitrile hydratase, known as Nhase-A20V. This mutant demonstrates a half-life of approximately 10 minutes at 70° C., maintaining thermal stability comparable to the wild enzyme. Notably, the specific enzyme activity of Nhase-A20V is 128% that of the wild enzyme. Additionally, this mutant exhibits improved tolerance to substrates and products, achieving a final yield of nicotinamide through whole-cell catalysis of 598 g/L. These properties indicate that Nhase-A20V has excellent enzymatic characteristics, making it advantageous for future industrial applications.

Career Highlights

Zhongyi Cheng is affiliated with Jiangnan University, where he continues to advance his research in enzyme engineering. His work not only contributes to academic knowledge but also has practical applications in various industries.

Collaborations

Zhongyi Cheng collaborates with notable colleagues, including Zhemin Zhou and Zhongmei Liu. Their combined expertise enhances the research output and innovation potential within their field.

Conclusion

Zhongyi Cheng's contributions to enzyme engineering, particularly through his patented mutant nitrile hydratase, highlight the importance of innovation in industrial applications. His work exemplifies how scientific advancements can lead to improved production processes and efficiency.