Zhonghan Li

Title: Zhonghan Li and Redox-Labile Fluorescent Probes

Introduction

Zhonghan Li is an inventor associated with Portland, Oregon, and the University of California. His patent work concerns fluorescent probes and methods for detecting metabolites, including lactate, in single cells.

Latest Patents

Li is named on 1 patent: “Redox-Labile Fluorescent Probes and Their Surface Immobilization Methods for the Detection of Metabolites.” The invention describes profiling lactate or other analyte production in single cells using coupled enzyme reactions involving surface-grafted resazurin and resorufin molecules. It also covers surface-bound indicators that retain redox activity and microfluidic devices incorporating those indicators.

Career Highlights

The available information identifies Li’s work with the University of California and his contribution to research tools for metabolite detection. The patent focuses on immobilizing fluorescent redox indicators on surfaces for use in analytical methods and microfluidic devices.

Collaborations

Min Xue and Hanjun Cheng are listed as Li’s coworkers. Their names are also associated with the collaborative research reflected in the patent.

Conclusion

Zhonghan Li’s patent contribution centers on surface-immobilized fluorescent probes that support single-cell metabolite analysis, particularly lactate detection.