The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Jul. 08, 2019
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Wei Wei, Seattle, WA (US);
Min Xue, Chino Hills, CA (US);
Zhonghan Li, Portland, OR (US);
Hanjun Cheng, Seattle, WA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); C09B 62/78 (2006.01); C09K 11/07 (2006.01); C12Q 1/26 (2006.01); C12Q 1/32 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54353 (2013.01); B01L 3/502761 (2013.01); C09B 62/78 (2013.01); C09K 11/07 (2013.01); C12Q 1/26 (2013.01); C12Q 1/32 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0893 (2013.01); B01L 2300/123 (2013.01); C09K 2211/1018 (2013.01);
Abstract
Disclosed herein is an analytical method for profiling lactate (or other analyte) production in single cells, via the use of coupled enzyme reactions on surface-grafted resazurin/resorufin molecules is provided. Additionally surface-bound resazurin/resorufin that retains redox indicator activity as well as microfluidic devices comprising such surface-bound resazurin/resorufin indicators are provided.