Chadds Ford, PA, United States of America

Zhixiong Xue

This inventor holds 49 USPTO granted patents and 9 published patent applications, plus 13 CIPO patents and 20 EPO patents, primarily in Polyunsaturated Fatty Acids. Top assignee: E.i. Dupont De Nemours and Company. Active years: 2005-2017.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Zhixiong Xue. Retrieved from https://idiyas.com/inventor/zhixiong-xue

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 49 (Patent Applications = 9)

% Patents Active = 42.9

CIPO Patents = 13 (Patent Applications = 10)

EPO Patents = 20 (Patent Applications = 19)

Average Co-Inventor Count = 3.4

ph-index = 8

Forward Citations = 472(Granted Patents)

Company Filing History:

49 out of 16,339

E.i. Dupont De Nemours and Company

patents

Years Active: 2005-2017

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Areas of Expertise:

Lipid Production

Oleaginous Yeast

Polyunsaturated Fatty Acids

Delta-9 Elongases

Sorbitol Utilization

Eicosapentaenoic Acid

Desaturases

Transcription Factors

Gene Expression

Microbial Oils

Peroxisome Biogenesis

Recombinant Microorganisms

49 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 9617571 - Peroxisome biogenesis factor protein (Pex) disruptions for altering polyunsaturated fatty acids and total lipid content in oleaginous eukaryotic organisms (2017-04-11),

2. 9441209 - Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells (2016-09-13),

3. 9175318 - Reducing byproduction of malonates by yeast in a fermentation process (2015-11-03),

4. 9150874 - Delta-9 elongases and their use in making polyunsaturated fatty acids (2015-10-06),

5. 9005940 - Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells (2015-04-14),

6. 8969049 - [object Object] (2015-03-03),

7. 8916365 - [object Object] (2014-12-23),

8. 8865429 - Increased oil content by increasing Yap1 transcription factor activity in oleaginous yeasts (2014-10-21),

9. 8859849 - Delta-8 desaturases and their use in making polyunsaturated fatty acids (2014-10-14),

10. 8822185 - Peroxisome biogenesis factor protein (PEX) disruptions for altering polyunsaturated fatty acids and total lipid content in oleaginous eukaryotic organisms (2014-09-02),

11. 8815566 - [object Object] (2014-08-26),

12. 8735108 - [object Object] (2014-05-27),

13. 8703473 - Recombinant microbial host cells for high eicosapentaenoic acid production (2014-04-22),

14. 8685682 - Docosahexaenoic acid producing strains of yarrowia lipolytica (2014-04-01),

15. 8685681 - Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms (2014-04-01),

Title: Zhixiong Xue: Innovator in Lipid Biogenesis

Introduction

Zhixiong Xue is an accomplished inventor based in Chadds Ford, PA, with an impressive portfolio of 49 patents. His work focuses primarily on advancements in lipid biogenesis, particularly in the context of oleaginous eukaryotic organisms. Xue's innovative approaches have made significant contributions to the fields of biotechnology and bioengineering.

Latest Patents

Among his latest patents is a groundbreaking method for altering polyunsaturated fatty acids (PUFAs) and total lipid content in oleaginous eukaryotes through peroxisome biogenesis factor protein disruptions. This invention outlines methods for increasing the amount of PUFAs in both the total lipid and oil fractions of PUFA-producing eukaryotes. By disrupting specific chromosomal Pex genes, the patent demonstrates a marked increase in PUFAs, enhancing the lipid profiles of these organisms compared to their non-disrupted parental strains.

Additionally, Xue has developed a recombinant microbial cell that utilizes down-regulation of the Sou2 sorbitol utilization protein to further modify lipid production. This innovation aims to increase overall lipid content while reducing sugar alcohol production in microbial cells, paving the way for more efficient oil production containing omega-3 polyunsaturated fatty acids, such as EPA.

Career Highlights

Zhixiong Xue is currently employed at E.I. du Pont de Nemours and Company, a firm renowned for its commitment to innovation and technological advancement. Throughout his career, Xue has continuously focused on enhancing the understanding and applications of lipid biogenesis, making valuable contributions to both academia and industry.

Collaborations

At E.I. du Pont de Nemours and Company, Xue collaborates with esteemed colleagues, including Quinn Qun Zhu and Narendra S. Yadav. Together, they push the boundaries of research in lipid biotechnology, demonstrating the power of teamwork in driving innovation.

Conclusion

Zhixiong Xue's contributions to the field of lipid biogenesis are noteworthy. With a strong track record of patents and ongoing research, he continues to impact the biotechnological landscape significantly. His work not only advances scientific understanding but also holds promise for developing new methods of sustainable oil production, highlighting the importance of innovative thinking in addressing contemporary challenges.

Profile summary based on public USPTO records.