The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2015
Filed:
Dec. 15, 2009
Applicants:
Quinn Qun Zhu, West Chester, PA (US);
Zhixiong Xue, Chadds Ford, PA (US);
Inventors:
Quinn Qun Zhu, West Chester, PA (US);
Zhixiong Xue, Chadds Ford, PA (US);
Assignee:
E. I. DUPONT DE NEMOURS AND COMPANY, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/64 (2006.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
C12P 7/6427 (2013.01); C12N 9/93 (2013.01); C12P 7/6472 (2013.01);
Abstract
Described are methods of reducing the amount of byproduct organic acids during fermentation of an organism, based on expression of a heterologous malonyl-CoA synthetase. A polyunsaturated fatty acid ['PUFA']-producing strain of the oleaginous yeastwas engineered to express a heterologous malonyl-CoA synthetase gene. The expression did not effect the production of PUFAs, but did result in a reduced amount of malonates when compared to the amount of malonates produced in the parental strain not expressing malonyl-CoA synthetase.