Zhimei Du

Title: Zhimei Du - Innovator in Glycoform Profiles

Introduction

Zhimei Du is a notable inventor based in Bellevue, WA (US). He has made significant contributions to the field of biotechnology, particularly in the development of Fc-containing molecules. His work focuses on improving glycosylation characteristics, which are crucial for the large-scale production of therapeutic molecules.

Latest Patents

Zhimei Du holds a patent for "Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles." This invention relates to variant Fc-containing molecules, such as antibodies and Fc-fusion molecules, which possess glycosylation characteristics favorable for therapeutic applications. The patent describes compositions and methods aimed at enhancing glycosylation maturation and minimizing culture process-dependent effects of these molecules. By creating single and multiple amino acid substitutions within the Fc domain, the invention seeks to improve high mannose processing and glycosylation maturation.

Career Highlights

Zhimei Du is currently employed at Amgen Inc., a leading biotechnology company. His work at Amgen has allowed him to contribute to advancements in therapeutic molecule production. His expertise in glycoform profiles has positioned him as a valuable asset in the field of biotechnology.

Collaborations

Zhimei Du has collaborated with notable colleagues, including Pranhitha Reddy and Randal B Bass. These collaborations have further enhanced the research and development efforts in the area of Fc-containing molecules.

Conclusion

Zhimei Du's innovative work in glycoform profiles and Fc-containing molecules has the potential to significantly impact the biotechnology industry. His contributions are paving the way for more effective therapeutic solutions.