Introduction: Zhili Zheng, located in Gaithersburg, MD, is an accomplished inventor specializing in advancements related to cancer treatment. With a total of five patents to his name, he has made significant contributions to the field of immunology, particularly in the development of T cell receptors (TCRs) that target specific mutations associated with cancer.

Latest Patents: Zhili Zheng's latest innovations include two notable patents. The first, titled "Anti-KRAS-G12D T Cell Receptors," discloses an isolated or purified T cell receptor with specificity for the mutated KRAS gene, presented in the context of an HLA-Cw*0802 molecule. This invention also provides related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, and pharmaceutical compositions. Additionally, it outlines methods for detecting the presence of cancer in mammals and for treating or preventing cancer. The second patent, "Methods of Isolating Neoantigen-Specific T Cell Receptor Sequences," describes techniques for isolating paired TCR alpha and beta chain sequences, along with methods for preparing populations of cells that express these sequences.

Career Highlights: Zhili Zheng works under the United States of America as represented by the Secretary of the Department of Health and Human Services. His innovative work has played a crucial role in enhancing the understanding and treatment options for cancer patients through immunotherapy.

Collaborations: Throughout his career, Zhili Zheng has collaborated with notable colleagues, including Yong-Chen Lu and Steven A Rosenberg. These collaborations have furthered research efforts in the field of T cell therapy and have contributed to the development of novel therapeutic strategies.

Conclusion: Zhili Zheng's contributions to the realm of cancer treatment through his innovative patents highlight his commitment to advancing medical science. His work not only showcases his expertise but also the potential for emerging therapies that could greatly impact cancer care. With ongoing research and collaboration, Zheng continues to pave the way for future innovations in immunotherapy.

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