Zhichao Xue

Title: Zhichao Xue and an Artificial Cell for Single-Cell Mass Spectrometry

Introduction

Zhichao Xue is an inventor based in Beijing, China, and is associated with the National Institute of Metrology, China. His listed patent focuses on an artificial cell designed for single-cell mass spectrometry measurement.

Latest Patents

Xue is named on one patent: “Artificial Cell for Single-Cell Mass Spectrometry (SCMS) Measurement and Preparation Method Thereof.” The invention describes an artificial cell with an internal aqueous phase containing polyethylene glycol (PEG) and polyvinyl alcohol (PVA), an intermediate oil phase made from a chloroform-hexane mixture containing L-α-phosphatidylcholine, and an external aqueous phase containing PVA and an F-68 aqueous solution.

The disclosure presents microfluidic self-assembly as a way to produce artificial single cells with improved uniformity, stability, and controllability compared with natural cell samples. These properties may help reduce measurement differences among individual samples and address challenges in preserving biological samples. Xue’s listed patent portfolio comprises 1 patent.

Career Highlights

Xue’s recorded innovation connects artificial-cell preparation with single-cell mass spectrometry, a measurement approach that examines individual cells. His association with the National Institute of Metrology, China, places this work within an institutional setting focused on measurement science.

Collaborations

Siyuan Tan and Xiaoyun Gong are identified as Xue’s coworkers. The available information does not specify their roles in the patent or the invention.

Conclusion

Zhichao Xue’s listed patent presents a microfluidically assembled artificial cell intended to support more consistent and stable single-cell mass spectrometry measurements.