Company Filing History:
Years Active: 2009-2013
Title: Innovations and Contributions of Inventor Zhi-Hong Li
Introduction
Zhi-Hong Li is a prominent inventor based in Burlingame, CA, known for his significant contributions to the field of drug development. With a total of eight patents to his name, he has made remarkable advancements in creating drug-ligand conjugates and methods for treating cancer.
Latest Patents
Among his latest patents, Zhi-Hong Li has developed drug-ligand conjugates that serve as potent cytotoxins. These conjugates link the drug to the ligand through various types of linkers, including peptidyl, hydrazine, or disulfide linkers. His work also includes methods of treating cancer using antibody-drug conjugates, which feature analogues of duocarmycins that are effective cytotoxins. The innovative linkers he has created are designed to be cleaved in vivo, facilitating the formation of prodrugs and conjugates that enhance therapeutic efficacy.
Career Highlights
Zhi-Hong Li has established a successful career at Medarex Inc., where he has been instrumental in advancing research and development in the pharmaceutical industry. His expertise in drug conjugation and cancer treatment has positioned him as a key figure in the field.
Collaborations
Throughout his career, Zhi-Hong Li has collaborated with notable colleagues, including Sanjeev Gangwar and Howard P Ng. These partnerships have contributed to the success of his projects and the advancement of innovative therapies.
Conclusion
Zhi-Hong Li's work exemplifies the impact of innovation in drug development and cancer treatment. His patents and collaborations reflect a commitment to improving therapeutic options for patients.