The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2010
Filed:
May. 19, 2005
Sharon E. Boyd, San Bruno, CA (US);
Liang Chen, San Mateo, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Vincent Guerlavais, Oakland, CA (US);
Killian Horgan, San Jose, CA (US);
Zhi-hong LI, Burlingame, CA (US);
Bilal Sufi, Santa Clara, CA (US);
Sharon E. Boyd, San Bruno, CA (US);
Liang Chen, San Mateo, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Vincent Guerlavais, Oakland, CA (US);
Killian Horgan, San Jose, CA (US);
Zhi-Hong Li, Burlingame, CA (US);
Bilal Sufi, Santa Clara, CA (US);
Medarex, Inc., Princeton, NJ (US);
Abstract
The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine, or disulfide linker. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.