The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2009
Filed:
May. 19, 2005
Applicants:
Liang Chen, San Mateo, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Vincent Guerlavais, Oakland, CA (US);
Zhi-hong LI, Burlingame, CA (US);
Bilal Sufi, Santa Clara, CA (US);
Inventors:
Liang Chen, San Mateo, CA (US);
Sanjeev Gangwar, San Mateo, CA (US);
Vincent Guerlavais, Oakland, CA (US);
Zhi-Hong Li, Burlingame, CA (US);
Bilal Sufi, Santa Clara, CA (US);
Assignee:
Medarex, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/403 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present disclosure provides drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-cleavable substrate conjugates, and to methods of treatment using them.