Zhan'ao Yang

Title: Zhan'ao Yang: Innovator in Pharmaceutical Crystallization

Introduction

Zhan'ao Yang is a notable inventor based in Shenzhen, China. He has made significant contributions to the field of pharmaceutical sciences, particularly in the area of crystallization methods for drug compounds. His innovative work has led to the development of a unique crystal form of cefazolin sodium pentahydrate, which has important implications for drug formulation and delivery.

Latest Patents

Zhan'ao Yang holds a patent for "Cefazolin sodium pentahydrate crystal and its molecular assembly preparation method." This invention relates to the preparation of cefazolin sodium pentahydrate crystal, which contains five water molecules and is characterized by an orthorhombic system with a space group of C222(1). The sodium ion is bonded to the cefazolin molecule through a coordinate bond. The method involves adding a solvent to a reactor, incorporating cefazolin acid and a sodium salt, and controlling various parameters to achieve a crystal with adjustable particle size, good flowability, smooth surface, high crystallinity, and rapid dissolving rate.

Career Highlights

Throughout his career, Zhan'ao Yang has worked with prominent institutions, including Tianjin University and Shenzhen Gosun Pharmaceutical Co., Ltd. His experience in these organizations has allowed him to refine his expertise in pharmaceutical research and development.

Collaborations

Zhan'ao Yang has collaborated with notable colleagues such as Yuxin Qian and Jiehua Wu. Their combined efforts have contributed to advancements in the field of pharmaceutical crystallization.

Conclusion

Zhan'ao Yang's innovative work in the preparation of cefazolin sodium pentahydrate crystal showcases his expertise and dedication to improving pharmaceutical formulations. His contributions are valuable to the industry and highlight the importance of research in drug development.