Zehao Pan

Title: Innovations of Zehao Pan in Cell Encapsulation and PCR Technology

Introduction

Zehao Pan is an accomplished inventor based in South Bend, IN (US). He has made significant contributions to the fields of cell encapsulation and polymerase chain reaction (PCR) technology. With a total of 2 patents, his work has the potential to revolutionize various applications in biomedical research and diagnostics.

Latest Patents

One of Zehao Pan's latest patents is a method of encapsulating single cells utilizing an alternating current electrospray. This innovative technique allows for the encapsulation of single cells with an efficiency exceeding 80%. The method employs natural and synthetic hydrogels, such as alginate, collagen, and NorHA, to protect the encapsulated cells from the host's immune response. Additionally, the coating facilitates improved tissue growth in laboratory cell cultures by providing conformal mechanical support that enables molecular and nutrient transport.

Another notable patent is related to AC electrosprayed droplets for digital and emulsion PCR. This invention utilizes alternating current electrospray technology to generate micron-sized droplets in oil at an exceptionally high throughput for emulsion or digital PCR. The technology significantly outperforms the current gold standard in droplet generation, achieving a throughput that is at least 100 times greater. The design is straightforward and can produce a billion to a trillion monodispersed droplets in about one hour, which is much faster than traditional flow-focusing methods.

Career Highlights

Zehao Pan is affiliated with the University of Notre Dame Du Lac, where he continues to advance his research and innovations. His work has garnered attention for its practical applications in various scientific fields.

Collaborations

He has collaborated with notable colleagues, including Hsueh-Chia Chang and David B Go, to further enhance the impact of his inventions.

Conclusion

Zehao Pan's innovative approaches in cell encapsulation and PCR technology demonstrate his commitment to advancing scientific research. His contributions are paving the way for new possibilities in biomedical applications and diagnostics.