The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2025

Filed:

Dec. 03, 2021
Applicant:

University of Notre Dame Du Lac, South Bend, IN (US);

Inventors:

Hsueh-Chia Chang, South Bend, IN (US);

Zehao Pan, South Bend, IN (US);

Vivek Yadav, South Bend, IN (US);

Loan Bui, South Bend, IN (US);

Donny Hanjaya-Putra, South Bend, IN (US);

Assignee:

UNIVERSITY OF NOTRE DAME DU LAC, South Bend, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/077 (2010.01); C12N 5/09 (2010.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0012 (2013.01); C12N 5/0652 (2013.01); C12N 5/0693 (2013.01); C12N 13/00 (2013.01); C12N 2533/30 (2013.01); C12N 2533/54 (2013.01); C12N 2533/74 (2013.01); C12N 2537/10 (2013.01);
Abstract

Described herein is a method for encapsulating single cells using alternating current electrospray technology in tip streaming mode. The encapsulation efficiency is over 80% and natural (alginate, collagen) and synthetic (NorHA) hydrogels and various cell types can be used. The encapsulated cells can be implanted and are protected from the host's immune response. In addition, the coating allows better tissue growth in laboratory cell cultures with a conformal mechanical support that allows molecular and nutrient transport.


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