Naperville, IL, United States of America

Ze-Qi Xu


Average Co-Inventor Count = 5.1

ph-index = 3

Forward Citations = 43(Granted Patents)


Location History:

  • Naperville, IL (US) (1998 - 2003)
  • Woodridge, IL (US) (2003 - 2015)

Company Filing History:


Years Active: 1998-2015

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21 patents (USPTO):Explore Patents

Title: The Innovations of Ze-Qi Xu: A Pioneer in Drug Conjugate Chemistry

Introduction

Ze-Qi Xu is an accomplished inventor based in Naperville, IL, boasting an impressive portfolio of 21 patents. His cutting-edge work primarily focuses on drug conjugate chemistry, positioning him as a significant contributor to advancements in cancer treatment and other critical medical applications.

Latest Patents

Xu's latest patents showcase his inventive prowess in the field. One notable invention is centered on thiol-ene click chemistry for drug conjugates. This invention details linker molecules capable of conjugating a cellular recognition ligand at one end with a drug payload at the other, proving useful in the treatment or prevention of cancer, autoimmune diseases, inflammatory conditions, central nervous system disorders, or infections. The structures of the linker molecules are represented by Formulas I, II, and III, while the Linker-Drug compounds are depicted by Formulas IV, V, and VI. Ligand-Linker-Drug conjugates are illustrated in Formulas VII, VIII, and IX.

Another significant patent involves indolocarbazole anticancer agents and methods of using the same. This invention pertains to the creation of anti-tumor compounds and compositions, particularly focusing on indolocarbazole analogues that inhibit topoisomerase I activity, offering promising developments in cancer treatment.

Career Highlights

Throughout his career, Ze-Qi Xu has been associated with prominent organizations such as Sarawak Medichem Pharmaceuticals, Inc. and the University of Illinois. His experiences in these institutions have enhanced his expertise and fueled his innovative endeavors in drug development and chemistry.

Collaborations

Xu has collaborated with notable coworkers, including Michael T. Flavin and John D. Rizzo. These partnerships have undoubtedly contributed to his success in developing effective pharmaceutical solutions.

Conclusion

Ze-Qi Xu stands out as a leading inventor in drug conjugate chemistry, with a remarkable contribution marked by his 21 patents. His innovative approaches to addressing complex medical challenges, particularly in cancer treatment, underlines the significance of his work in the scientific community. As he continues to explore new horizons in the field, Xu's legacy as a pioneer in innovation is firmly established.

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