The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2003

Filed:

Aug. 15, 2001
Applicant:
Inventors:

John M. Pezzuto, River Forest, IL (US);

Jerome W. Kosmeder, II, Oak Park, IL (US);

Ze-Qi Xu, Naperville, IL (US);

Nian En Zhou, Naperville, IL (US);

Miriam Elaine Goldsmith, Naperville, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/156 ; C07J 5/300 ;
U.S. Cl.
CPC ...
A61K 3/156 ; C07J 5/300 ;
Abstract

A composition and method of preventing or inhibiting tumor growth and, more particularly, of treating a malignant tumor, using prodrugs of plant-derived compounds and derivatives is disclosed. In the method, a composition containing betulinic acid or a betulinic acid derivative is administered in a prodrug form to release betulinic acid or a betulinic acid derivative in vivo at the tumor site.


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