Los Angeles, CA, United States of America

Yvonne Y Chen

USPTO Granted Patents = 6 

 

Average Co-Inventor Count = 2.8

ph-index = 2

Forward Citations = 10(Granted Patents)


Company Filing History:


Years Active: 2021-2025

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6 patents (USPTO):Explore Patents

Title: **Yvonne Y. Chen: Pioneering Innovation in Chimeric Antigen Receptors**

Introduction

Yvonne Y. Chen, a prominent inventor based in Los Angeles, California, has made significant contributions to the field of biomedical engineering and immunotherapy. With a total of six patents to her name, Chen’s innovative work focuses primarily on chimeric antigen receptors (CAR), which are crucial for developing targeted therapies against various cancers, particularly B cell malignancies.

Latest Patents

Among her latest innovations is the bispecific OR-gate chimeric antigen receptor responsive to CD20 and CD19. This groundbreaking invention features a CD20-OR-CD19 CAR protein construct capable of triggering T-cell activation upon detecting either CD19 or CD20, or both. The invention includes nucleic acids encoding this CAR and outlines methods for its use, especially in treating B cell malignancies. This bispecific CAR represents a significant advancement as it enables enhanced recognition and response by human T cells engineered to express this CAR stably.

Career Highlights

Yvonne Chen has worked with prestigious institutions such as the University of California and Seattle Children’s Hospital, contributing her expertise to groundbreaking research and applications in immunotherapy. Her career is marked by her dedication to developing effective cancer treatments and her ability to pivot complex biological concepts into practical, innovative solutions.

Collaborations

Throughout her career, Chen has collaborated with notable professionals in her field, including colleagues Eugenia Zah and Michael C. Jensen. These partnerships have fostered a productive exchange of knowledge and have significantly impacted the advancement of her research efforts.

Conclusion

Yvonne Y. Chen stands out as an influential inventor whose work in the realm of chimeric antigen receptors has the potential to transform cancer treatment. With her innovative spirit and collaborative approach, she continues to contribute valuable insights and techniques that enhance the efficacy of immunotherapeutic strategies. Her contributions underscore the importance of innovation in science and medicine, driving forward the quest for effective solutions to complex medical challenges.

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