This inventor holds 1 USPTO granted patent. Top assignee: Technical University of Denmark. Active years: 2018.
Company Filing History:
Years Active: 2018
Title: Innovations of Yun Chen in Microbial Production
Introduction
Yun Chen is an accomplished inventor based in Kgs. Lyngby, Denmark. He has made significant contributions to the field of microbial production, particularly in the synthesis of 3-hydroxypropionic acid. His innovative work has implications for various industrial applications, showcasing the potential of yeast cells in biotechnological processes.
Latest Patents
Yun Chen holds a patent for the microbial production of 3-hydroxypropionic acid. The patent describes a yeast cell that has a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH). This yeast cell incorporates at least one exogenous gene encoding NADP dependent GAPDH and/or exhibits up-regulation of at least one endogenous gene expressing NADP dependent GAPDH. The combined expression of the enzymes NADP dependent GAPDH, PDC, ALD, ACS, ACC*, and MCR in the host cell enhances metabolic flux towards 3-HP via malonyl-CoA compared to a similar yeast cell lacking these genetic modifications. This innovation represents a significant advancement in metabolic engineering.
Career Highlights
Yun Chen is affiliated with the Technical University of Denmark, where he conducts research and development in the field of biotechnology. His work focuses on enhancing microbial processes for the production of valuable chemicals. His expertise and innovative approaches have positioned him as a key figure in his research community.
Collaborations
Yun Chen collaborates with notable colleagues, including Niels Bjerg Jensen and Irina Borodina. These collaborations foster a dynamic research environment, allowing for the exchange of ideas and advancements in their respective fields.
Conclusion
Yun Chen's contributions to microbial production and his innovative patent highlight the potential of biotechnology in creating sustainable solutions. His work continues to inspire advancements in the field, paving the way for future innovations.