Company Filing History:
Years Active: 2016-2025
Title: Yumin Yang: Innovator in Tissue Engineering
Introduction
Yumin Yang is a prominent inventor based in Jiangsu, China. He has made significant contributions to the field of tissue engineering, particularly in the development of nerve grafts. With a total of 4 patents, his work focuses on enhancing the repair efficiency of nerve cells.
Latest Patents
Yumin Yang's latest patents include groundbreaking innovations in the construction and application of differentially regulated tissue-engineered nerve grafts. This invention features a differential tissue-engineered nerve that includes both motor-like and sensory-like nerves. Each type of nerve comprises an outer tube and a fiber, with Schwann cells and/or fibroblasts derived from the respective nerves contained within the outer tubes. Additionally, transsynaptic signal molecules Neuroligin-1 and Neuroligin-2 are integrated into the nerve fibers to promote synaptic remodeling, thereby improving the repair efficiency of motor and sensory nerve cells.
Another notable patent is the construction of MicroRNA gene-mediated novel tissue-engineered nerves. This invention utilizes specific MicroRNA genes to enhance the repair of peripheral nerve defects. The tissue-engineered nerve grafts are coated with polymeric nanomicrospheres that carry miRNA inhibitors, promoting the proliferation of Schwann cells and providing an anti-apoptotic effect on neuronal cells. In-vivo tests have demonstrated that these grafts facilitate the regeneration of peripheral nerves, proving their utility in treating nerve injuries.
Career Highlights
Yumin Yang is affiliated with Nantong University, where he continues to advance research in tissue engineering. His innovative approaches have garnered attention in the scientific community, contributing to the understanding and treatment of nerve injuries.
Collaborations
Yumin Yang has collaborated with notable colleagues, including Xiaosong Gu and Fei Ding, to further enhance the impact of his research in the field of tissue engineering.
Conclusion
Yumin Yang's contributions to tissue engineering, particularly in nerve repair, highlight his role as an influential inventor. His innovative patents and ongoing research continue to pave the way for advancements in medical treatments for nerve injuries.