Location History:
- Taichung, RC (1977)
- Taichung, CT (1978)
- Taichung, TW (1979)
- San Jose, CA (US) (1979 - 1992)
Company Filing History:
5 out of 444 
4 out of 7,865 
1 out of 22 Years Active: 1977-1992
Title: Celebrating Innovations by Yuh-Geng Tsay in Biotechnology
Introduction: Yuh-Geng Tsay, an inventive mind based in San Jose, California, has made significant contributions to the field of biotechnology. With a remarkable portfolio of 14 patents, his work primarily focuses on developing advanced methodologies for detecting specific DNA sequences and antibodies in various samples. Tsay's inventions have not only enhanced diagnostic capabilities but have also paved the way for innovative research applications.
Latest Patents: Among his latest breakthroughs are two notable patents: the "DNA Probe Diffraction Assay and Reagents" and the "Fluorometric Assay of Chymopapain Hypersensitivity and Reagents Therefor." The DNA probe diffraction assay utilizes DNA sequences as probes in a nucleic acid hybridization diffraction assay. This method detects specific DNA sequences in a sample, employing diffraction assay methodologies to ascertain the presence and quantity of analytes. Tsay's invention involves improved supporting surfaces for biogrids or biogratings, which notably reduce non-specific hybridization and binding. His innovative processes include manufacturing biogratings by adhering a uniform layer of hybridizing reagent to a smooth, solid surface and selectively deactivating the hybridizing reagent using UV radiation.
The other significant patent focuses on identifying and quantifying chymopapain-specific IgE antibody levels in patient serum. This method involves binding the IgE in serum to chymopapain on an insoluble support, tagging it with a labeled anti-IgE antibody, and measuring the resulting levels. These patented methods significantly contribute to allergy diagnosis and treatment monitoring.
Career Highlights: Yuh-Geng Tsay has worked with prominent organizations, including Research Incorporated and Minnesota Mining and Manufacturing Company (3M). His roles in these companies have allowed him to apply his innovative ideas in practical settings, leading to the development of impactful biotechnological solutions.
Collaborations: Throughout his career, Tsay has collaborated with other outstanding professionals in the field. Notably, he has worked alongside Emanuel Calenoff and Andrew S. Kende. These collaborations have enabled the exchange of ideas and further advancements in their shared areas of expertise.
Conclusion: Yuh-Geng Tsay's innovative contributions to biotechnology showcase his dedication to enhancing scientific understanding and diagnostic capabilities. With each patent, he brings forth groundbreaking solutions that not only propel research but also provide profound benefits to healthcare. His ongoing work continues to inspire future generations of inventors and researchers in the field.