Vancouver, Canada

Yuan-Peng Zhang


Average Co-Inventor Count = 5.2

ph-index = 7

Forward Citations = 1,197(Granted Patents)


Location History:

  • Mountain View, CA (US) (2000 - 2004)
  • Sunnyvale, CA (US) (2005)
  • Vancouver, CA (1998 - 2008)

Company Filing History:


Years Active: 1998-2008

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7 patents (USPTO):Explore Patents

Title: Innovations of Yuan-Peng Zhang

Introduction

Yuan-Peng Zhang is a prominent inventor based in Vancouver, Canada. He has made significant contributions to the field of gene transfer technology, holding a total of seven patents. His work focuses on the development of lipid-nucleic acid particles that enhance the delivery of genetic material for therapeutic purposes.

Latest Patents

One of his latest patents is titled "Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer." This patent describes novel lipid-nucleic acid particulate complexes that are useful for both in vitro and in vivo gene transfer. The particles can be formed using either detergent dialysis methods or methods that utilize organic solvents. Upon the removal of a solubilizing component, such as detergent or an organic solvent, the lipid-nucleic acid complexes form particles that are serum-stable and protected from degradation. These particles have access to extravascular sites and target cell populations, making them suitable for the therapeutic delivery of nucleic acids. Another significant patent is the "Method of preventing aggregation of a lipid:nucleic acid complex." This patent outlines a technique to prevent particle aggregation by incorporating a non-cationic lipid into lipid:nucleic acid complex particles that contain a cationic lipid and a nucleic acid polymer. The non-cationic lipid used is a polyethylene glycol-based polymer.

Career Highlights

Yuan-Peng Zhang has worked with notable organizations, including Inex Pharmaceuticals Corporation and the University of British Columbia. His experience in these institutions has allowed him to advance his research and contribute to the field of biotechnology.

Collaborations

He has collaborated with esteemed colleagues such as Marcel B Bally and Dorothy L Reimer, further enhancing the impact of his work in the scientific community.

Conclusion

Yuan-Peng Zhang's innovative work in the development of lipid-nucleic acid particles has the potential to revolutionize gene transfer technologies. His contributions are significant in advancing therapeutic applications in biotechnology.

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