San Diego, CA, United States of America

Yuan Liu

USPTO Granted Patents = 29 

 

 

Average Co-Inventor Count = 6.5

ph-index = 14

Forward Citations = 484(Granted Patents)


Company Filing History:


Years Active: 2017-2025

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29 patents (USPTO):

Title: Yuan Liu: Innovator in Cancer Treatment

Introduction

Yuan Liu is a notable inventor based in San Diego, CA, with a remarkable portfolio of 28 patents. His work primarily focuses on innovative compounds designed to inhibit specific proteins that are implicated in cancer progression, particularly the G12C mutant KRAS protein.

Latest Patents

Among Yuan Liu's recent patents are two significant inventions. The first is centered on "Substituted piperazines as inhibitors of KRAS G12C." This patent describes compounds capable of modulating the activity of the G12C mutant KRAS protein, along with their pharmaceutical applications in treating various disorders, including cancer. The structure of these compounds offers potential for therapeutic efficacy in targeted cancer therapies.

The second patent involves "Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer." Similar to his prior work, this invention also focuses on inhibiting the G12C mutant KRAS protein, providing detailed methodologies linked to the preparation and application of these compounds in pharmaceutical compositions aimed at cancer treatment.

Career Highlights

Throughout his career, Yuan Liu has made significant contributions to the field of medicinal chemistry and targeted cancer therapies. He has held positions in reputable companies, including Araxes Pharma LLC and Janssen Biotech, Inc., where he applied his expertise to bridge the gap between pharmaceutical innovation and practical medical solutions.

Collaborations

Yuan Liu has collaborated with esteemed colleagues such as Liansheng Li and Pingda Ren. Their joint efforts exemplify a shared commitment to advancing research and developing effective treatments for challenging medical conditions, notably in cancer therapeutics.

Conclusion

Yuan Liu stands as a prominent figure in the field of medical inventions, particularly with his groundbreaking patents that target the G12C mutant KRAS protein involved in cancer. His work not only showcases his inventive spirit but also reflects the collaborative ethos essential in advancing medical research and innovation for the benefit of society.

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