This inventor holds 3 USPTO granted patents and 4 published patent applications. Top assignee: National Taiwan University. Active years: 2012-2014.
Company Filing History:
Years Active: 2012-2014
Title: Innovations of Yu-Chun Chien in Medical Imaging
Introduction
Yu-Chun Chien is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of medical imaging, particularly in the development of algorithms for monitoring chemotherapy response and early detection of breast cancers. With a total of 3 patents, his work is paving the way for advancements in cancer treatment assessment.
Latest Patents
One of Yu-Chun Chien's latest patents is the "Longitudinal image registration algorithm for infrared images for chemotherapy response monitoring and early detection of breast cancers." This innovative algorithm provides a marker-free approach to establishing pixel correspondence among infrared images taken at different times. It quantitatively characterizes the variation of heat energy and patterns on a breast surface. The algorithm utilizes corner points of heat patterns and branch points of skeletons on the body surface as initial fiducial points for longitudinal infrared image registration. The Thin-Plate Spline technique models the nonlinear deformation between two infrared images taken at different times, while mutual information quantifies the quality of the registration. To optimize this process, the Nelder-Mead simplex method is employed to modify the pairings of fiducial points in the source and target images.
Another significant patent is the "Dual-spectrum heat pattern separation algorithm for assessing chemotherapy treatment response and early detection." This algorithm quantifies energy from high-temperature tissues, referred to as qmap, and decomposes the body surface into high and normal temperature areas based on middle-wave and long-wave infrared images. With longitudinal registration, it can detect cancerous tissues and assess chemotherapy treatment response on a pixel-by-pixel basis. Preliminary results indicate that the area and q-values in high-temperature areas decrease as patients undergo more chemotherapy, suggesting the algorithm's potential for effective chemotherapy assessment and early detection.
Career Highlights
Yu-Chun Chien is affiliated with National Taiwan University, where he continues to innovate in the field of medical imaging. His work has garnered attention for its potential impact on cancer treatment and monitoring.
Collaborations
Yu-Chun Chien collaborates with notable colleagues, including Chung-Ming Chen and Si-Chen Lee, contributing to the advancement of medical imaging technologies.
Conclusion
Yu-Chun Chien's innovative work in developing algorithms for infrared imaging represents a significant advancement in the early detection and monitoring of breast cancer. His contributions are vital