Location History:
- Sakai, JP (1995 - 1996)
- Osaka, JP (1998)
Company Filing History:
Years Active: 1995-1998
Title: Innovations of Yoshiyuki Yamada
Introduction
Yoshiyuki Yamada is a notable inventor based in Sakai, Japan. He has made significant contributions to the field of chemistry, particularly in the production of amino acid derivatives. With a total of three patents to his name, Yamada's work has implications for the pharmaceutical industry.
Latest Patents
Yamada's latest patents include a process for producing glutamine derivative, specifically N-chloroacetylglutamine. This compound is produced by reacting chloroacetyl chloride with an alkaline aqueous solution of glutamine in the presence of a water-immiscible organic solvent. The process involves separating an aqueous layer through liquid-liquid separation and crystallizing N-chloroacetyl-glutamine from the aqueous layer under acidic conditions. This innovation allows for the efficient and cost-effective production of N-chloroacetyl-glutamine, which serves as an intermediate for producing glycyl-L-glutamine, a compound known for its higher stability compared to L-glutamine and its use in infusion solutions.
Another significant patent by Yamada is the process for producing alanylglutamine. This process involves reacting an N-(2-substituted)-propionylglutamine compound with ammonia at a temperature of 60 degrees Celsius or below. The method ensures the production of highly purified alanylglutamine in high yield without racemization, showcasing Yamada's expertise in chemical synthesis.
Career Highlights
Yoshiyuki Yamada is associated with Kyowa Hakko Kogyo Co., Ltd., a company known for its advancements in biotechnology and pharmaceuticals. His work at the company has been instrumental in developing innovative processes that enhance the production of valuable compounds.
Collaborations
Yamada has collaborated with notable coworkers, including Kazumi Amatsu and Shoichi Mizutaki. Their combined efforts have contributed to the success of various projects within the company.
Conclusion
Yoshiyuki Yamada's contributions to the field of chemistry through his innovative patents highlight his role as a significant inventor. His work not only advances scientific knowledge but also has practical applications in the pharmaceutical industry.