Location History:
- Kodaira, JA (1978)
- Izumi, JP (1980)
- Gotenba, JP (1999 - 2011)
- Tokyo, JP (1987 - 2014)
Company Filing History:
6 out of 950 
1 out of 9 
1 out of 12 
Years Active: 1978-2014
Title: Innovations by Yoshiyuki Ohsugi
Introduction
Yoshiyuki Ohsugi is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of medical science, particularly in the area of transplantation and rheumatoid arthritis treatment. With a total of 6 patents to his name, Ohsugi's work has the potential to improve patient outcomes in critical health conditions.
Latest Patents
Ohsugi's latest patents include groundbreaking methods for suppressing acute rejection of heart transplants. His research examined the effect of anti-IL-6 receptor antibodies in suppressing cytotoxic T cell induction. The results indicated that CTL activity against alloantigens was statistically significantly reduced in mice treated with these antibodies compared to untreated mice and those treated with a control antibody. Furthermore, in a mouse model for allogenic heart transplantation, the administration of anti-IL-6 receptor antibodies led to a suppression of inflammatory cell infiltration into transplanted hearts, significantly prolonging the survival period of these organs. This discovery marks a significant advancement in the understanding of how to mitigate acute rejection after transplantation.
Another notable patent addresses chronic rheumatoid arthritis therapy, which includes an IL-6 antagonist as an effective component. This pharmaceutical composition serves as a synovial cell growth inhibitor, providing a new avenue for treating chronic rheumatoid arthritis. The inclusion of IL-6 antibodies or IL-6R antibodies as effective components highlights the innovative approach Ohsugi has taken in developing treatments for debilitating conditions.
Career Highlights
Throughout his career, Yoshiyuki Ohsugi has worked with notable companies, including Chugai Pharmaceutical Co., Ltd. and Tadamitsu Kishimoto. His experience in these organizations has allowed him to collaborate with leading experts in the field, further enhancing his contributions to medical science.
Collaborations
Ohsugi has collaborated with esteemed colleagues such as Masahiko Mihara and Tadamitsu Kishimoto. These partnerships have played a crucial role in advancing his research and patent developments.
Conclusion
Yoshiyuki Ohsugi's innovative work in the fields of transplantation and rheumatoid arthritis treatment showcases his dedication to improving patient care through scientific advancements. His patents reflect a commitment to addressing critical health challenges, making him a significant figure in medical innovation.