Location History:
- Osaka, JP (2005)
- Tsuruga, JP (1996 - 2015)
- Fukui, JP (2012 - 2015)
Company Filing History:
23 out of 789 
2 out of 1,112 
2 out of 150 
Years Active: 1996-2015
Title: Yoshiaki Nishiya: A Pioneer in Enzyme Innovations
Introduction
Yoshiaki Nishiya, hailing from Tsuruga, Japan, has established himself as a formidable inventor with a remarkable portfolio of 26 patents. His innovative contributions primarily revolve around the fields of enzyme research and biochemistry, showcasing his expertise in developing high-performance proteins with practical applications in diagnostics and analysis.
Latest Patents
Among Nishiya's latest patents is a novel alkaline phosphatase (AP) that boasts high specific activity and superior reactivity with various luminescent substrates. This invention is particularly beneficial for high-sensitivity immunoassay analysis. The alkaline phosphatase derived by Nishiya exhibits several remarkable characteristics, including a molecular weight of approximately 104,000, an optimum reaction pH of around 9.5, and thermal stability up to 65°C. It also demonstrates a specific activity of 5,000 U/mg or more, making it a significant advancement in the field of enzyme applications.
Another groundbreaking patent addresses a protein exhibiting fructosyl valyl histidine oxidase activity, which is instrumental in measuring glycosylated proteins, notably glycosylated hemoglobin. This invention includes a modified version of the protein, characterized by excellent thermal stability and substrate specificity. These properties enhance the accuracy and longevity of glycosylated protein measuring reagents, further demonstrating Nishiya's commitment to improving diagnostic tools.
Career Highlights
Yoshiaki Nishiya has contributed significantly to renowned companies such as Toyo Boseki and Hitachi Maxell, Limited. His work in these organizations has paved the way for advancements in enzyme technology, significantly influencing both research and industry practices.
Collaborations
Throughout his career, Nishiya has collaborated with notable colleagues, including Masao Kitabayashi and Yoshihisa Kawamura. These partnerships have enriched his research and fostered a collaborative spirit that has been vital in driving forward innovations in enzyme applications.
Conclusion
With a robust collection of patents and a commitment to advancing enzyme technology, Yoshiaki Nishiya stands as a prominent figure in biochemical innovations. His contributions not only enhance the scientific community but also positively impact the practical applications of enzyme technology in diagnostic processes. As he continues to work on groundbreaking inventions, Nishiya's future in the field promises to be as innovative as his past.