Location History:
- Guangzhou, CN (2019)
- Guangdong, CN (2019)
Company Filing History:
Years Active: 2019
Title: Yong Dong: Innovator in Regenerative Medicine
Introduction
Yong Dong is a prominent inventor based in Guangzhou, China. He has made significant contributions to the field of regenerative medicine, particularly in the areas of T cell regeneration and bone marrow microenvironment remodeling. With a total of 2 patents, his work is paving the way for advancements in hematologic treatments.
Latest Patents
Yong Dong's latest patents include a method for regenerating T cells and a method for remodeling the bone marrow microenvironment. The first patent describes a method for inducing the transdifferentiation of B lymphoid cells into T lymphoid cells using the transcription factor Hoxb5. This innovative approach involves introducing Hoxb5 or a related nucleic acid molecule into B lymphoid cells, leading to the generation of T cell progenitor cells that can differentiate into mature T cells. The regenerated T cells are functionally normal and exhibit a very low risk of tumorigenesis.
The second patent focuses on a method for remodeling the bone marrow microenvironment in subjects with impaired conditions. This method involves implanting a composition of isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity. This technique successfully restores normal hematopoiesis, inhibits the progression of leukemia, and significantly extends survival periods for patients. It is a safe and effective treatment for hematologic tumors such as leukemia and aplastic anemia.
Career Highlights
Yong Dong is affiliated with the Chinese Academy of Sciences, where he conducts his research and development. His work has garnered attention for its potential to transform treatment protocols in regenerative medicine.
Collaborations
Yong Dong collaborates with notable colleagues, including Jinyong Wang and Chengxiang Xia. Their combined expertise enhances the research and development efforts in their respective fields.
Conclusion
Yong Dong's innovative work in regenerative medicine, particularly through his patents on T cell regeneration and bone marrow microenvironment remodeling, showcases his commitment to advancing medical science. His contributions are vital for improving treatment options for patients with hematologic disorders.