Yizhong Jin

Title: Yizhong Jin: Innovator in Biocatalysis and Pharmaceutical Intermediates

Introduction

Yizhong Jin is a prominent inventor based in Zhejiang, China, known for his contributions to the field of biocatalysis and pharmaceutical intermediates. With a total of three patents to his name, he has made significant advancements in the synthesis of important chemical compounds.

Latest Patents

One of his latest patents is titled "Transaminase mutant and application thereof in preparation of sitagliptin intermediates." This invention discloses a transaminase mutant that is engineered through specific amino acid substitutions. The method utilizes either wet cells or a purified transaminase as a biocatalyst to prepare sitagliptin intermediates, achieving a total yield of approximately 82% and an enantiomeric excess value of 99%. Another notable patent is the "Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof," which outlines a systematic approach to synthesize this compound.

Career Highlights

Yizhong Jin has worked with notable organizations such as Zhejiang Yongtai Technology Co., Ltd. and Zhejiang University. His experience in these institutions has allowed him to refine his skills and contribute to innovative research in the field of chemistry.

Collaborations

Throughout his career, Yizhong Jin has collaborated with esteemed colleagues, including Renbao He and Hongming Shao. These partnerships have fostered a collaborative environment that enhances the development of new technologies and methodologies.

Conclusion

Yizhong Jin's work in biocatalysis and pharmaceutical intermediates showcases his innovative spirit and dedication to advancing chemical synthesis. His patents reflect a commitment to improving methods that have significant implications in the pharmaceutical industry.