Ying-Chih Chang

Title: **Ying-Chih Chang: Innovator in Biological Substance Capture and Purification**

Introduction

Ying-Chih Chang is a prominent inventor based in Taipei, Taiwan, known for his significant contributions to the field of biotechnology. With a total of six patents to his name, his innovations focus on the capture, purification, and release of biological substances, specifically targeting circulating tumor cells. His work has implications in cancer research and diagnostics, providing valuable tools for the medical community.

Latest Patents

Chang's latest patents include groundbreaking inventions that enhance the efficiency of capturing rare biological cells. One of his notable patents involves a surface coating designed to capture circulating rare cells. This innovative surface coating comprises a nonfouling composition that prevents the binding of non-specific cells and the adsorption of serum components. It also features a bioactive composition aimed at binding biological substances, such as circulating tumor cells, potentially with a linker composition for enhanced effectiveness.

Another remarkable invention is a novel microfluidic chip incorporating specifically patterned microstructures that create flow disturbances, thereby increasing the capture rate of biological substances. This advancement can significantly improve the processes involved in isolating and studying rare cells.

Additionally, Chang developed cell culture substrates with associated systems and methods for their manufacturing and usage, further exemplifying his commitment to advancing biotechnological applications.

Career Highlights

Ying-Chih Chang is associated with Academia Sinica, a leading research institution in Taiwan. His role at this prestigious organization allows him to contribute to significant advancements in research and innovation. His expertise in developing innovative solutions for capturing and purifying biological substances has positioned him as a leading figure in his field.

Collaborations

Throughout his career, Chang has collaborated with notable professionals, including Jen-Chia Wu and Han-Chung Wu. These partnerships have fostered an environment of innovation and have contributed to the success of his research efforts and patent developments.

Conclusion

Ying-Chih Chang stands out as an influential inventor in the biotechnology sector, with his extensive portfolio of patents reflecting his dedication to improving the methodologies for handling biological substances. His work not only advances scientific knowledge but also holds promise for practical applications in medical diagnostics and research.