This inventor holds 3 USPTO granted patents and 2 published patent applications. Top assignee: Princeton University. Active years: 2006-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2006-2010
Title: Yigong Shi: Innovator in Apoptosis Research
Introduction
Yigong Shi is a prominent inventor based in Plainsboro, NJ (US). He has made significant contributions to the field of apoptosis research, holding a total of 3 patents. His work focuses on developing compounds that can influence cellular processes, particularly those related to programmed cell death.
Latest Patents
One of Yigong Shi's latest patents involves IAP binding compounds. These compounds are designed to bind cellular IAPs, or inhibitors of apoptosis proteins. They are mimetics of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABOLO, IIid, Grim, and Reaper. These proteins interact with a specific surface groove of IAP, and the patent also includes methods for using these compounds in therapeutic, diagnostic, and assay applications. Another notable patent is for soluble, functional apoptotic protease-activating factor 1 fragments. This patent discloses the structure of a soluble, functional fragment of the human Apaf-1 protein with ADP bound to it. The invention encompasses methods for creating these fragments and their applications in screening methods to identify adenine nucleotide analogs and other compounds that may help alleviate or prevent disease conditions linked to improper regulation of apoptosis.
Career Highlights
Yigong Shi is affiliated with Princeton University, where he continues to advance research in his field. His innovative work has garnered attention and respect within the scientific community, contributing to a deeper understanding of apoptosis and its implications for health and disease.
Collaborations
Yigong Shi has collaborated with notable colleagues, including George McLendon and Rachael A Kipp. These partnerships have further enriched his research endeavors and expanded the impact of his inventions.
Conclusion
Yigong Shi's contributions to apoptosis research through his patents and collaborations highlight his role as a leading inventor in the field. His work not only advances scientific knowledge but also holds potential for therapeutic applications that could benefit many.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile