The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2010
Filed:
Jul. 15, 2003
George Mclendon, Durham, NC (US);
Rachael A. Kipp, Bridgewater, MA (US);
Martin Case, Essex Junction, VT (US);
Yigong Shi, Plainsboro, NJ (US);
Martin F. Semmelhack, Princeton, NJ (US);
Philip A. Albiniak, Muncie, IN (US);
Aislyn D. Wist, West Orange, NJ (US);
George McLendon, Durham, NC (US);
Rachael A. Kipp, Bridgewater, MA (US);
Martin Case, Essex Junction, VT (US);
Yigong Shi, Plainsboro, NJ (US);
Martin F. Semmelhack, Princeton, NJ (US);
Philip A. Albiniak, Muncie, IN (US);
Aislyn D. Wist, West Orange, NJ (US);
The Trustees of Princeton University, Princeton, NJ (US);
Abstract
Compounds that bind cellular IAPs (inhibitor of apoptosis proteins) are disclosed. The compounds are mimetics of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABOLO, IIid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these compounds for therapeutic, diagnostic and assay purposes.