Yi Zheng

Title: Yi Zheng and Multiplexed Imaging with Nanobody Probes.

Introduction

Yi Zheng is an inventor based in Dover, Massachusetts, and is associated with Akoya Biosciences, Inc. His patent work includes a method for multiplexed imaging that uses nanobody probes to identify different protein targets in a biological sample.

Latest Patents

Zheng is named on 1 patent: “Multiplexed Imaging with Nanobody Probes.” The method contacts a biological sample with multiple probe types, each designed to bind selectively to a different protein target. Each probe includes a detection moiety, a nanobody, and a linked oligonucleotide with a sequence unique to that probe type. The sample is then contacted with optical labels whose oligonucleotides selectively hybridize to particular probe types, enabling the targets to be distinguished through imaging.

Career Highlights

Zheng’s listed patent reflects work in multiplexed biological imaging, combining target-selective probes with oligonucleotide-based optical labeling. He is associated with Akoya Biosciences, Inc.

Collaborations

The provided information lists Julia Kennedy-Darling and Peter J. Miller as Zheng’s coworkers. Their names indicate professional connections, but no specific joint patent or collaboration details were provided.

Conclusion

Yi Zheng’s patent describes a nanobody-based approach to multiplexed imaging that uses distinct oligonucleotide sequences and optical labels to distinguish protein targets in biological samples.