Yeli Zhang

Title: Yeli Zhang: Pioneering Innovations in Drug Delivery and Tablet Technology

Introduction

Yeli Zhang is a distinguished inventor based in Somerville, NJ, recognized for his significant contributions to the fields of pharmaceuticals and innovative excipient technologies. With a remarkable portfolio of eight patents to his name, Zhang's work focuses on enhancing drug delivery systems and developing more effective solid dosage forms.

Latest Patents

Among his recent innovations, Zhang has developed a groundbreaking composition known as a "tablet excipient." This invention pertains to a composition that includes physically modified, partially pregelatinized starch. This multi-functional excipient is designed for solid dosage forms, characterized by its unique properties such as a predominance of birefringent and non-birefringent portions, alongside a sedimentation volume ranging from 1.5 to 9 ml/g. His composition demonstrates remarkable cold water solubility levels between 1 and 8% and can yield free-flowing starch with an average particle size greater than 30 micrometers, exhibiting a moisture content of 5 to 12% by weight. A notable achievement is the 500 mg placebo tablet fabricated from this composition, which meets industry standards with a crushing strength of at least 160 Newtons and a disintegration time of no more than 10 minutes.

Another significant patent by Zhang involves a hydrogel formulated to entrap therapeutic agents, alongside a vascular stent featuring a coating of this advanced hydrogel. This unique system comprises a hydrophobic macromer and a polysaccharide-based hydrophilic polymer that allows for controlled release of therapeutic agents. The hydrogel's three-dimensional crosslinked polymer network is capable of trapping drugs and macromolecules, thereby optimizing their delivery within the body.

Career Highlights

Zhang has collaborated with esteemed organizations throughout his career, notably working at the Cornell Research Foundation Inc. and Corn Products Development, Inc. His innovative approach and commitment to advancing pharmaceutical technology have earned him recognition and respect in the industry.

Collaborations

During his career, Zhang has partnered with talented individuals, including coworkers Chee-Youb Won and Chih-Chang Chu, sharing knowledge and expertise that have contributed to the significant advancements in his research and inventions.

Conclusion

Yeli Zhang's inventive spirit and dedication to pharmaceutical innovation continue to shape the landscape of drug delivery systems and tablet technology. His cutting-edge patents reflect a commitment to improving patient outcomes through advanced formulations. Through his work, Zhang exemplifies the transformative power of innovation in the health and wellness industry.