Kobe, Japan

Yasushi Shirahase

USPTO Granted Patents = 7 


Average Co-Inventor Count = 2.9

ph-index = 2

Forward Citations = 24(Granted Patents)


Location History:

  • Hyogo, JP (2000 - 2003)
  • Kobe, JP (1992 - 2023)

Company Filing History:


Years Active: 1992-2023

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7 patents (USPTO):Explore Patents

Title: Yasushi Shirahase: Innovator in Enzymatic Measurement Technologies

Introduction

Yasushi Shirahase is a prominent inventor based in Kobe, Japan. He has made significant contributions to the field of enzymatic measurement, holding a total of seven patents. His work focuses on the development of methods and reagents that enhance the accuracy and efficiency of biochemical assays.

Latest Patents

One of Yasushi Shirahase's latest patents involves enzymes and reagents for the measurement of short-chain fatty acids. This invention discloses methods for the enzymatic measurement of fatty acids with three to six carbon atoms in various samples. The methods utilize recombinant butyrate kinases from multiple species, combined with various reagents, including ATP, to detect butyric acid through the measurement of ATP consumption. Additionally, the patent includes the reagents themselves.

Another notable patent is related to mitochondrial creatine kinase antibodies. This invention aims to provide a method for accurately assaying the enzyme activities of mCK isozymes. It allows for the separate assay of ubiquitous mCK (umCK) and sarcomeric mCK (smCK) enzyme activities using an antibody that specifically recognizes umCK protein. The patent also describes the use of other anti-mCK antibodies and provides a monoclonal antibody (U1-1881) that specifically recognizes human umCK.

Career Highlights

Yasushi Shirahase has worked with several reputable companies, including International Reagents Corporation and Sysmex Corporation. His experience in these organizations has contributed to his expertise in the field of enzymatic measurement technologies.

Collaborations

Throughout his career, Yasushi has collaborated with notable individuals such as Yoshifumi Watazu and Kazuaki Yamashita. These collaborations have further enriched his work and innovations in the field.

Conclusion

Yasushi Shirahase is a distinguished inventor whose contributions to enzymatic measurement technologies have advanced the field significantly. His innovative patents and collaborations reflect his commitment to enhancing biochemical assays and improving scientific research methodologies.

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