Location History:
- Tokyo, JP (2015)
- Sakura, JP (2018)
Company Filing History:
Years Active: 2015-2018
Title: Yasuhide Hirota: Innovator in Polynucleotide Research
Introduction
Yasuhide Hirota is a prominent inventor based in Sakura, Japan. He has made significant contributions to the field of molecular biology, particularly in the development of polynucleotides that exhibit resistance to RNase and possess RNA interference effects. With a total of 2 patents, his work is paving the way for advancements in genetic research and therapeutic applications.
Latest Patents
Hirota's latest patents include a double-stranded polynucleotide designed to provide resistance to RNase while facilitating RNA interference. This invention comprises sense and antisense strands made up of polynucleotides that alternate between DNA and 2'-O-methyl RNA units. Additionally, he has developed modified single-stranded polynucleotides that also resist RNase and have RNA interference capabilities. This invention features a single-stranded polynucleotide derived from a double-stranded counterpart, linking the 5'-end of the antisense strand and the 3'-end of the sense strand through a phenyl group-containing linker, forming a phosphodiester structure.
Career Highlights
Hirota is currently associated with Daiichi Sankyo Company, Limited, where he continues to innovate in the field of biotechnology. His research focuses on enhancing the efficacy of polynucleotides for therapeutic use, contributing to the advancement of genetic medicine.
Collaborations
Throughout his career, Yasuhide Hirota has collaborated with notable colleagues, including Makoto Koizumi and Makiko Nakayama. These partnerships have fostered a collaborative environment that enhances the research and development of innovative solutions in molecular biology.
Conclusion
Yasuhide Hirota's contributions to the field of polynucleotide research are noteworthy, with his inventions holding promise for future advancements in genetic therapies. His work exemplifies the impact of innovation in biotechnology, paving the way for new treatments and research methodologies.