Yasufumi Ohfune

Title: Yasufumi Ohfune: Innovator in Mass Spectrometry and Organic Chemistry

Introduction

Yasufumi Ohfune is a prominent inventor based in Takatsuki, Japan. He has made significant contributions to the fields of mass spectrometry and organic chemistry. With a total of 7 patents to his name, Ohfune's work has advanced the understanding and analysis of nitrogen-containing organic compounds.

Latest Patents

One of his latest patents is a mass spectrometric method for structural analysis of chain nitrogen-containing compounds using squaric acid. This innovative method effectively causes charge-remote fragmentation (CRF) during the structural analysis of nitrogen-containing organic compounds. The technique utilizes high-energy collisional-induced dissociation-mass/mass spectrum (CID-MS/MS spectrum) to enhance the analysis process. The method involves introducing a squaric acid residue into the end of a nitrogen-containing organic compound, which is represented by a specific chemical formula. Additionally, he has developed a reagent for this method and a comprehensive approach for analyzing organic compounds through the induction of CRF.

Another notable invention by Ohfune is related to optically active 1-amino-2-hydroxycycloalkanecarboxylic acid derivatives. This invention focuses on compounds that can fix the conformation of peptide or protein molecules when introduced in place of a normal amino acid. The synthesis methods and applications of these compounds further highlight Ohfune's expertise in organic chemistry.

Career Highlights

Throughout his career, Yasufumi Ohfune has worked with reputable companies, including Suntory Limited and Suntory Holdings Limited. His experience in these organizations has contributed to his innovative research and development efforts in the field of chemistry.

Collaborations

Ohfune has collaborated with notable colleagues, including Masahiro Sakaitani and Keiko Shimamoto. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in their respective fields.

Conclusion

Yasufumi Ohfune's contributions to mass spectrometry and organic chemistry have established him as a leading inventor in his field. His innovative methods and collaborations continue to influence the scientific community and pave the way for future advancements.