Yaping He

Title: Yaping He: Innovator in HPV Vaccine Development

Introduction

Yaping He is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of biotechnology, particularly in the development of vaccines against human papillomavirus (HPV). His innovative work focuses on identifying linear B-cell epitopes that can be utilized in vaccine formulations.

Latest Patents

Yaping He holds a patent titled "Minimal motifs of linear B-cell epitopes in L1 protein from human papillomavirus type 58 and their applications." This patent discloses eighteen linear epitope motifs and their extended 8-mer peptides in the L1 protein from HPV 58. These motifs can be used as antigens to specifically detect serum from subjects infected with HPV 58. Furthermore, they can aid in the development of preventive or therapeutic multi-epitope peptide vaccines against HPV 58 by inducing humoral immunity. Among the eighteen B-cell epitope motifs, ten are 100% conservative, while one is highly conservative among many homologous proteins of high-risk HPVs. These motifs serve as candidate 'universal' epitopes for developing HPV vaccines.

Career Highlights

Yaping He is associated with Hengsun Pharmaceutical Technology Co. Ltd., where he continues to advance his research in vaccine development. His work has the potential to significantly impact public health by providing effective preventive measures against HPV infections.

Collaborations

Yaping He collaborates with notable colleagues, including Wanxiang Xu and Shaohua Gu. Their combined expertise enhances the research and development efforts within their organization.

Conclusion

Yaping He is a key figure in the innovation of HPV vaccine development, with a focus on linear B-cell epitopes. His contributions are vital for advancing preventive healthcare solutions against HPV infections.