Yangong Han

Title: Innovations in Drug Synthesis: The Contributions of Yangong Han

Introduction

Yangong Han is a notable inventor based in Beijing, China. He has made significant contributions to the field of drug synthesis, particularly through his innovative methods for preparing pharmaceuticals. His work has implications for the development of effective medications, showcasing the importance of research and innovation in healthcare.

Latest Patents

Yangong Han holds a patent for a method of preparing lornoxicam. This method involves using 6-chloro-4-hydroxy-2-methyl-2-H-thieno[2,3-e]-1,2-thiazine methyl carboxylate-1,1-dioxide and 2-aminopyridine as raw materials, with xylene as a solvent. The process includes mixing the raw materials and solvent, adding a stabilizer, and subjecting the mixture to ammonolysis. The resulting reactant is cooled, and the solvent is removed through vacuum concentration. An organic solvent is then added, and the mixture is filtered to obtain crude lornoxicam, which is subsequently refined to yield the final product. The use of p-toluenesulfonic acid as a stabilizer is a key aspect of this method, as it reduces the reaction temperature and enhances the quality and yield of lornoxicam.

Career Highlights

Yangong Han is associated with Beijing Jincheng Taier Pharmaceutical Co., Ltd., where he continues to contribute to advancements in pharmaceutical synthesis. His expertise in drug development has positioned him as a valuable asset in the industry.

Collaborations

Yangong Han has worked alongside colleagues such as Zhen Liu and Dongye Xing, contributing to a collaborative environment that fosters innovation and research in drug synthesis.

Conclusion

Yangong Han's contributions to the field of drug synthesis, particularly through his patent for preparing lornoxicam, highlight the critical role of inventors in advancing healthcare solutions. His work exemplifies the intersection of innovation and pharmaceutical development, paving the way for future advancements in the industry.